Hi,
There is nothing magical nor particularly difficult or unusual about the chemistry of these compounds, and in fact they have been studied to death in the real world. Simply what is happening is heavy metal pollution and the natural analogue is an industriallized embayment. As these situations have a lot of human heath concerns, they has been well studied. It is all there on the web or in your local EPA library for you to cogitate over.
These heavy metals are sequestered by organisms to detoxify them, or they go into the sediments as various ionic compounds, many of which are insoluble (= precipitates) at the higher pH's of reef tanks. They tend to remain in the sediments "waiting" until the pH drops, if that does, many of them will go into solution - and in the closed environment of an aquarium - they would form a lethal soup.
So... you can have a tank with a toxic soup in the water, and some heavy metal sludge in the sediments. And this whole system looks grand, because that is what we are used to.
Then if you have an accident, say a calcium reactor burps too much carbon dioxide into the system, and the pH does a transient drop. If that drop is low enough, it cause some of the metals to become soluble. These could cause immediate problems - including mortality. If the pH returns to normal in short order, the metals become insoluble again, and if you tested for them you would never see them. However, animals would have been killed. Another "mystery" death....