I have had my tank setup since around March of this year.
Bioballs are notorious for being nitrate (waste) traps that can throw your water quality in the crapper.
Same with the sponge. Once you see them you will realize they are impossible to clean because they are so thick. I have heard of people cutting the sponge in half and making it easier to get the debris out of it but for me it's much easier to simply pull out the used filter floss when I do my weekly water changes and replace it with new filter floss than it is to worry about the sponge.
Of course there is more than 1 way to run these setups and I'm sure people use some of the media that comes with the nano's but for me this makes sense.
Here's a bit on both purigen & chemi-pure (info from Dr. Foster & Smith where I buy these products):
http://www.drsfostersmith.com/product/Shop.cfm?N=2004
Purigen
A macro-porous, synthetic polymer that removes proteins, nitrite and nitrate, ammonia, and a broad spectrum of organics at a rate and capacity that exceeds all others by over 500%. It significantly raises redox and polishes water clarity.
Chemi-Pure
* Easily remove dissolved organics and enjoy sparkling water
* Maintain a perfect pH level in any water type
* Enjoy minimal replacement hassles
Your fish will live a healthier life â€"œ up to 4 times longer. Works equally well in marine or freshwater aquariums to remove heavy metals, copper, phenol, ammonia and other nitrogenous waste. Helps keep pH at a consistently safe range and your water sparkling clear. Fantastic for use with African Cichlids and Discus. Use one 10 ounce unit, already packed in a filter bag, for up to 40 gallons. Remains active for 4-6 months.
Regular carbon in no way even comes close to doing half of what these do. Plus the purigen can be regenerated and the chemi-pure has a longer life than regular carbon.
I started off with just chemi-pure and after adding the purigen I noticed a huge change in the water quality, I'll never go without
I'd go skimmerless to start. If you feel that you need the skimmer later you can always add it.
Again though, with these tanks if you ask 100 people how they run them you will get 100 unique answers.