I went skimmerless about 2 weeks ago. It's too soon to really comment on my success, so I'll wait longer.
I'm trying to focus on running a diverse refugium. I have a small piece of rock with Aiptasia to filter feed, along with chaeto and halymedia to fight nitrates. My pod population has exploded and my refugium is full of creepy crawlies. I also began running a filter sock that I rinse out every 4-5 days just to minimize particulate matter in the water. I'm doing 5 gallon water changes every week on a 40 gallon breeder with 20L sump. Total water volume is roughly 45 gallons.
I feed once a day, tiny pinch of Spectrum pellets.
I keep a gigantea carpet anemone (fed frequently), a few acros, a birdsnest, deresa clam, and some mushroom corals. Fish bioload is very light: 2 perculas, 1 chromis, and 1 sharknose goby.