Help me chloroquine users...
- Thread starter Stuginski
- Start date
rossco838
New member
From what I understand 3-4 week treatment and 1 day is not enough time to see any improvement, I think after a week they should be clinically free of the disease. I'm sure someone will correct me if I'm wrong. I am about to start a chloroquine treatment in my 275 gallon fowlr system
MrTuskfish
Team RC
Thnks rossco...
I'm really concerned about this fish....I want that him restore the shape and appetite as fast as possible.
Hails from brazil
D.
The appearance and disappearance of ich spots doesn't mean anything. Most of the ich life cycle is invisible. I'd read the ich life-cycle stickies in the disease forum and re-post this in that section. You need to know the parasites life-cycle to understand what's going on. One day mans nothing. Have some patience; there is nothing you can do to speed up the process.
jd474
New member
I'd treat @ 15 mg/l. Ideally you could test, and re-dose every 48 hours, as necessary, as it is somewhat light sensitive and breaks down relatively quickly, but I doubt you own a spec that can test chloroquine. If you have a moderate to heavy infestation, chloroquine generally won't clear it up. It is pretty effective if you treat prophylactically, or catch the problem early, and/or can test your levels to re-dose as needed. Also make sure you store your powder in the dark, as ambient light can render it ineffective.
Hi Tusk. How are u?
Yes I know that spots just represent one of the ich phases and I already read the stickies but I read to that Chloroquine affect all phases of protozan's life cicle....so...spots decreasing seems to be a good indicative of the effectivity of the treatment. Am I wrong?
Hi Jd. How are you? 15mg/l...re dosing every 48 hours? Wow it seems much more than one shot approach with 10mg/l that some folks are doing. Have you tryed this before?
I bought my Cholorique direct from the pharmacy. I would get a copper shot...but...cupramine and coppersafe are prohibited in Brazil...as many other medicines. I already tryed hypo before with bad results (severe bloating and ich survive)...so...i will try CP.
Until now...48 hours...zero improvement...let's wait a week. I just hope that my fish can handle with a week without feeding :-(
D.
Yes I know that spots just represent one of the ich phases and I already read the stickies but I read to that Chloroquine affect all phases of protozan's life cicle....so...spots decreasing seems to be a good indicative of the effectivity of the treatment. Am I wrong?
Hi Jd. How are you? 15mg/l...re dosing every 48 hours? Wow it seems much more than one shot approach with 10mg/l that some folks are doing. Have you tryed this before?
I bought my Cholorique direct from the pharmacy. I would get a copper shot...but...cupramine and coppersafe are prohibited in Brazil...as many other medicines. I already tryed hypo before with bad results (severe bloating and ich survive)...so...i will try CP.
Until now...48 hours...zero improvement...let's wait a week. I just hope that my fish can handle with a week without feeding :-(
D.
MrTuskfish
Team RC
I have not used chloroquine yet; I plan to, as soon as a little LFS gets a good candidate for me. I avoid commenting on the med for that reason. I will comment on ich and treatment though, as long as the question seems in line with something I might think I know and is not specific to the med. I'm convinced that this stuff is sure worth trying, some very good hobbyists use it. I am not convinced that chloroquine kills ich on/in the fish or kills ich cysts. I've heard/read opinions both ways from people that know a lot more than I do. I am a little leery of using a med that can't be easily tested. As jd474 said above. Quinine sulfate, a close relative of chloroquine, is hard to keep in suspension and I assume folks who use it have found a way to control that. Even if a med killed the ich in/on the fish; I wouldn't think the spots would be gone immediately.
If the fish is feeding, breathing well, etc; I would just let the med do its work. If the fish is still going downhill or looks near death; then worry. In the mean time, maybe you can PM one of the folks who are more familiar with the drug.
If the fish is feeding, breathing well, etc; I would just let the med do its work. If the fish is still going downhill or looks near death; then worry. In the mean time, maybe you can PM one of the folks who are more familiar with the drug.
MrTuskfish
Team RC
I'm still not up to speed on chloroquine; but why would you cut back feeding? i'm guessing ammonia concerns. I'm still a copper user and am very comfortable with it and I feed as much as the fish will eat; and siphon out uneaten food. IMO, a fish needs all the help he can get because of the med and ich combination.
MrTuskfish
Team RC
Not skimming for 6+ weeks wouldn't hurt anything; especially if you siphon uneaten food and that should be done anyhow. (easy in a bare bottom qt) and have an adequately cycled bio-filter to control ammonia. Nitrates may rise, but that's no big deal. Nitrates don't hurt fish (at least at any level seen in in a QT). I don't even see a reason to test nitrate in a HT/QT.
jd474
New member
15 mg/l is the standard dosage for a lot of public aquariums. Because it breaks down quickly, we dose a bit higher to keep doses at effective levels (~10 ppm) for longer periods. If you can test and re-dose as necessary this is best, but I doubt any hobbyist owns a Hach DR6000 or similar spec that can test chloroquine (most professional facilities don't). You can also do water changes, and calculate your dose for what you need to replace. Blacking out the tank may also help, but I don't recommend the stress on your fish. FWIW, I've never seen any oral chloroquine or anti-protozoal medications being done/recommended by a vet. Not sure why it would even be considered, to be honest.
I would like to see the public aquarium protocols. Chloroquine is very stable in solution unless you are introducing sunlight or some other high intensity source into your aquarium. Why would you do that to a QT or hospital tank?
THe LD50 is not very far from the therapeutic dose. I have yet to read a protocol recommending a dose of 15 ppm and the info I just read stated a dose of 8 -10 ppm in the public aquaria setting. I have not tried your dosing regimen, so maybe you are correct, but I have also not not have problems with treatment failures at a strict 10 ppm.
As for oral dosing - You could try it as an experiment, but really do not know what benefit you plan to achieve and I don't know of any science behind it.
As for the bumps from ich - how long does it typically take for the red bump to go away after you are bitten by a mosquito or fly?
THe LD50 is not very far from the therapeutic dose. I have yet to read a protocol recommending a dose of 15 ppm and the info I just read stated a dose of 8 -10 ppm in the public aquaria setting. I have not tried your dosing regimen, so maybe you are correct, but I have also not not have problems with treatment failures at a strict 10 ppm.
As for oral dosing - You could try it as an experiment, but really do not know what benefit you plan to achieve and I don't know of any science behind it.
As for the bumps from ich - how long does it typically take for the red bump to go away after you are bitten by a mosquito or fly?
Thank you guys...
Now we have 3 days since I dose CP.
BUT...I have a problem...I don't turn off the skimmer completely (I just turn off 1 pump...50% turn off), because I was afraid about acumulation of ammonia (there are 3 other fishes in qt and all are eating very well)..so I don know if my shot was effective enough.
My water is very cloudy. But 0 ammonia (at least in toxic side).
My longnose still seems like a milanese steak but today he ate mysis and clams (not to much..but is better than nothing)
Do you think that I have to re dose and turn off my skimmer completely or just wait a few more days to discover if the CP was effective?
Thank you all
D.
Now we have 3 days since I dose CP.
BUT...I have a problem...I don't turn off the skimmer completely (I just turn off 1 pump...50% turn off), because I was afraid about acumulation of ammonia (there are 3 other fishes in qt and all are eating very well)..so I don know if my shot was effective enough.
My water is very cloudy. But 0 ammonia (at least in toxic side).
My longnose still seems like a milanese steak but today he ate mysis and clams (not to much..but is better than nothing)
Do you think that I have to re dose and turn off my skimmer completely or just wait a few more days to discover if the CP was effective?
Thank you all
D.
alprazo is correct, unless the chloroquine is being exposed to UV light, it is very stable in solution - a single dose can remain effective for 14 days or more. I generally use 10 mg/l as a preventative, but 15 mg/l for active disease. I've used 20 mg/l for persistant Uronema, but without much benefit. Definately continue to check the ammonia level following any chloroquine treatment.
-Bill
-Bill
rssjsb
New member
Actually, I thought CP is effective only at the tomite (free-swimming) stage of the ich parasite's life cycle. So the fact that you have not seen a difference in the fish at the trophont stage (i.e., the stage where the parasite is visible on the fish) may not mean anything.
MrTuskfish
Team RC
My understanding as well.
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