Tank size: Larger is better, of course, but managability is more important. Keeping water quality high, for 8 new anthias, which will probably require lots of food being thrown into the tank, can be easier in a smaller tank, since changing an entire 20g may be easier for you than changing 50 entire gallons. I would do a 20g myself.
Filtration: An established hang-on power filter is perfect. Also, keep a small powerhead in the tank for brisk circulation (cover the intake!!)
Aquascaping: Large PVR pipe segments works fine. Make sure they don't bounce around in the flow, though. IME this can freak out the fish.
Food: Whatever they will eat. Try TINY amounts at first to prevent fouling the water with uneaten food. Remove uneaten food as quickly as possible. I like hikari mysis, finely minced shrimp and scallop from the grocery store as first foods. A trick I use: throw the food into the flow of the powerhead. IME The quick movement of the food shooting through the water column often triggers an anthias feeding response (not that lyretails are terribly difficult).
Meds: I would prazi them. Otherwise, nothing unless needed. The idea of coppering fish becasue they may carry something like ich or velvet without showing signs, is a personal decision. Some people do, some don't.
Duration: I'd go 3-4 weeks if all looks good, especially if you do multiple prazi treatments.
HTH. GL, they are great fish!