Ideally you want to perform any treatment in a QT, it can be something as simple as a large rubbermaid with a hang on filter. Dropping the salinity down that much in a reef tank will have some consequences, while it may not affect the bio-filter much, it will ensure that every invert in the tank will die. Just because you don't have any snails, corals, or crabs, doesn't mean you don't have inverts....most likely you have thousands living in your sand and rock that you don't know about. When they die, there could be an ammonia spike that you're not ready for.
Hyposalinity is really quite simple, drop the sg down to 1.009 / salinity of 12ppt, and maintain it there for a few weeks. After that you just slowly bring the salinity back up to 35ppt and you're good to go.