I had this once MANY years ago (about 15 years ago). I did a LARGE water change (almost 1/3) and added carbon and it went away. But I did stir up the substrate with my water change (maybe it has something to do with a buildup in the substrate?). I cant tell you what it was, or what caused it. I just know thats how I fixed it. My fish had popeye too at that time, and that went away as well (less than a week). Hope someone else gives you better advice.
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