It isn't supersaturation of oxygen that is the issue, but rather supersaturation of nitrogen. Both can become supersaturated easily if a pump receives air on the intake side (sump microbubbles, a pin hole leak on the intake, etc.). For larger pumps and systems, this air is then pressurized in the return, forcing air into solution. When that pressure is released (in the display), your fish essentially can get the bends. Just like for scuba divers, excess oxygen isn't an issue as the body utilizes it quickly.
If you have higher head pressure (big pumps, a downstairs filtration room...), making sure no air gets to the intake side of your return pump is very important.