Can you give some history for this trigger? How long have you had him? Have you added any other (unquarantined) fish lately? I see you have an angel... what else is in the tank?
On the theory it might be from a trauma, do you have anything like an anemone that might have stung hum? Is he getting along OK with the other fish? Has he been scratching on something?
Unless you can identify a physical cause, you should plan to get him into a treatment tank.