how big is it, is the bottom being shaded. If not it might be RTN'd. I'd frag off as much of the living tissue as you can immediately before you lose the whole colony. go to the SPS forum to learn more....
The jury is out on causes, but bacteria infections are one of the leaders. Tissue balls up and seems to peel off of the colony in a webbed pattern in 24-48 hours max.
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