Are these Paly?

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Lol, button polyps. I think most would agree they are palythoa. So yeah, they could very well be toxic. Just wear gloves when you handle them and don't brush your skin against them if you can help it.
 
Those are very invasive growers. I wouldn't put them in your main rock work as they can take over, they also grow very thick mats where they grow on.
 
The Palythoas in the picture can hurt other zoas and corals in the tank.
They have a tremendous ability to take over the rocks, reproducing fast, and they should be left alone on they own rock.

Grandis.
 
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