I suppose their may be a way to calculate the load by looking at biomass. However, I am not aware of any way to definitively measure bioload. There are many critical elements that factor into the load a particular system faces and each system is unique.
Basically, each animal that produces waste adds to your bioload. The amount of waste directly correlates to how much you feed, temperature (metabolic rate), health, etc.
Uneaten foods also contribute to a bioload.
In a nutshell, it becomes a guessing game...bigger than a breadbox kinda thing.