Haven't tried a tank raised regal from blue zoo...
In my experience, pacific blue tangs are quite hardy. The problem is that they get way too big for most of our tanks, and they behave really strangely when in too small of a tank. They either get hyper aggressive, or they become really shy/depressed and hang out wedged into the rocks all day.
Like all tangs, they are susceptible to ich...Something about small scales and not much mucous production. I don't think that morphology would change in a captive raised, or even captive bred, specimen. Luckily though, ich is easily treated as long as you do it before it goes into your display.
I guess my advice to those looking at a pacific blue tang would be:
1. Have a large tank. A standard 180 to a standard 240 would be the range.
2. Either strict QT or prophylactic tank transfer method or both for the tang and all other incoming fishes.