I would use a router and build a plywood guide on the tank itself. I have actually done something like this myself, although I cut the tank the opposite way you are thinking of. I took an old 180 gallon and routed off the last 2' of so. I built a " fish room" in my garage to room ended up being 46" wide so I could use a standard 48" tank. I addition to cutting off the end I solvent glued a new piece of acrylic to the side and cut off the entire "eurobraced" piece on the top and solvent glued a new "eurobrace" frame on top.
I did all of this with a router and the right tooling (bits) A table saw usually has a blade mounted that has too few teeth if you cut acrylic with a circular saw of any type you need something with 99 or 100 teeth on a 10" or 12" blade.