You really only need one for incoming air-pushing air in. If you put one pushing it out, it will rust up. If you have air coming in and a hole nearly the same size it should all go out. But if you want to do it that way, I am sure it will work just fine. Put one hole on one end, and the other on the other end. I did mine on the back panel. I use the 6" Radio shack 120 volt fan. And I am sure you could cut a smooth hole with a Dremel, its just a lot smaller and weaker, so go slow.