Sequence pumps can be mounted vertically with no problem. I asked Sequence this question directly. However, last year I set up a guys 540 gallon tank with a hammerhead as the closed loop pump, installed vertically. Last week the pump failed. This was due to a leak on the seal allowing water to run down the shaft onto the bearings and into the motor housing. Sequence did send a new pump right away with instructions on returning the damaged pump. So you can mount them in this fashion but you run a greater risk of problems should they leak...... I was planning to mount mine vertically until this happened. Now I will mount it horizontally just to be safe....