Most food nowadays contain garlic in them, formular I & II and some flake. I add it directly to the food if I feel some thing isn't right in my tank otherwise I just feed the food that contains it like Spectrum Thera A Formula which my fish eat like crazy.
I'm not sure if it loses any effectiveness as it really is suppose to help the fish build and keep up it's immune system.
I tend to use Kent garlic in frozen food almost on a daily basis when I had my 90 gallon up and running. i will probably do the same when I have the 180 fully stocked. Some people claim that there is not an benefit to garlic, I tend to differ on that opinion.
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