One thing to be aware of if you're going with a "non-sterile" setup for zots is hydroid infestations, because they 'droids bloom due to the abundant amount of live food required to keep the zots fed. Hydroids can kill zots pretty easily.
You'll need to pre-mitigate this (most peeps use fenbendazole) or be ready to do a lot siphoning if they show up:
Lifted from the Disease & Treatment Forum of "the SH site that we can't mention here":
FENBENDAZOLE (granules) Dosage and Preparation Instructions Hydroids
Active Ingredient: Fenbendazole
Indication: hydroids
Brand Names: Panacur, Safe-Guard
Note: This treatment is ONLY recommended for Seahorse fry nurseries and Dwarf Seahorse tanks that
do NOT contain invertebrates/corals. (Nassarius sp. snails have been known to survive treatment).
Residual effects of this medication may make the tank inhospitable for invertebrates for up to two years
following treatment.
Dose at 1mg per gallon for light infestations.
Dose 2mg per gallon for heavy infestations.
Repeat every other day for three treatments.
• Purchase Fenbendazole granules available as 1gm packets.
• Thoroughly mix a single 1gm packet into 100ml of water. (100ml is equal to a little less than 1/2 cup).
Please note that the granules will not completely dissolve.
• This mixture will produce 2.22mg of Fenbendazole per ml.
• Add the appropriate dose to your tank.