In general I don't like systems with one powerhead because you have no back up should it fail. I do think the 6000 is the better option but keep a spare on hand for emergencies, even if it is just a couple mj 1200's. The 6000 will use the same amount of power, occupy less space than 2 6045s and has more options, not to mention it is upgradeable to a 6100 if you move up to a bigger tank.