Interceptor off the market

emm0909

New member
Anyone use Interceptor for parasites in the tank? I have and it works awesome. They had an issue with a batch last year (maybe two years) and I'd say for the last year or two people have been claiming that you can no longer get it. My vet always has it in stock.

Today I went to grab some meds for my dog and asked about the interceptor. They said that they were replacing it with Sentinel. Sentinel does all the same things as Interceptor except that it does not guard against ticks. Sentinel does however guard against fleas which Interceptor does not.

While I was there I picked up four doses of Interceptor for my tank just incase Sentinel doesn't work. I've never used Sentinel. Anyone?
 
I believe he is talking about a in tank treatment. Bayer advanced can only be used as a dip and not to treat the entire tank.
 
Word from other is that Interceptor is not comIng back, Sentinal is off the market but should soon return. Sentinal is the same ingredient as interceptor and Lavisomol (Milbemycin) with one other drug (lufenuron) a flea birth control I don't know the reef saftiness of the latter drug.
 
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It should be right with the other livestock medications; but maybe it's off the market too. I'll ask when my vet comes in from her morning chores in a couple.
 
Levamisole is back in powdered form. Maybe TS doesn't carry it any longer, but feed stores and other ag supply places should. A couple years ago I made a post comparison about it on another site that apparently become modded out.
 
Here's some work I did on this a couple years ago; I stopped working on it after a cost comparison showed that interceptor was a far better value. As a note: Ivermectin and Lavamisole should be interchangeable; I will confirm at that latter. At one point the Ivermectin was taken off the market perhaps were misusing it in their contraband.

[quote author=mr.msalty link=topic=13676.msg136193#msg136193 date=1283365824]
I've been doing some work on this, and will do more. We all know common treatment for red bugs. $20 for a few pills may not be much to pay when several hundred dollars of livestock may be irritated by this pest, but it is quite a bit more than you would pay for 12 pills* w/rebate for your dog or cat. Now here is the fun part the medicine in
Interceptor is in the same family as Ivermectin which is available in other commercial brand products and comes in a much easier to dose liquid form, and the my quick cost break down is roughly 21 23mg treatments for under $40. Better yet anyone can pick this up at your local farm supply store* :dancin:

This article seems a wee bit flawed IMO but that is irrelevant; here's the important part of it:
Ivermectin (Stromectolâ„¢, Ivomecâ„¢, HeartGardâ„¢, Iverhart Plusâ„¢, Tri-Heart Plusâ„¢ and Acarexxâ„¢)
Ivermectin is a treatment for lice, mites, ear mites and is also an antihelmitic (effective against roundworms, heartworms, and lungworms) in cattle and swine. It is also prescribed for humans as a treatment for Bancroft's filariasis and scabies.

Wright (2009) suggests this treatment protocol: Dissolve Ivomec (1% solution) in propylene gycol (an alcohol). Dose at 0.75 mg/l per gallon (actual volume). Wright's article used 34 mg in 45 gallons).

Turn off the protein skimmer, UV sterilizer, and canister filters and disperse the Ivomec solution in a strong stream of water within the aquarium. After 12 hours, filter water using fresh activated carbon and resume use of the protein skimmer and UV sterilization. Repeat this treatment every two weeks for a total of 3 times.

The author (Wright) cautions that this treatment might harm arthropods, mollusks, crustaceans, other invertebrates (I'm assuming he doesn't mean corals other than the Acropora specimen mentioned in the article) and angelfishes.


http://www.advancedaquarist.com/2010/3/corals

I don't think you want to use any of the "plus" meds, as there is something else in it. It also looks like the researcher used a paste form rather than an injectable solution, nevertheless the fundamentals are the same.


More to come...
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[quote author=mr.msalty link=topic=13676.msg136198#msg136198 date=1283386731]
OK. worked a few of the problems (other than using items "plus") with the above synopsis out: First was the use of injectable ivormectin vs topical and dissolving; the injectable tends to flocculate (precipitate) in water, hence using a vehicle for its dosing. Second, what in darn snivies is a .75 mg/l per gallon??? I've viewed Wright's abstract and the dose was that for any living organism which he took an entire reef aquarium to be 200 mcg/kg or 200 mcg/l, hence he prescribed a dose of 34 mg or 3.4 ml diluted in 10 ml of the mentioned alcohol to 45 gallons.

Turns out EB looked into this back in 06, though I haven't asked him his thoughts on it yet. Another DVM, DR. Weber* at Cal Davis mentioned one problem public aquaria has had dosing medications diluted in grain alcohol is "dramatic decrease in DO" This seems not in ready accord with current organic carbon dosing trends.
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[quote author=mr.msalty link=topic=13676.msg136200#msg136200 date=1283388729]
OK lets do a cost comparison before going further. Dorton's Mibemycin Oxime protocol is 23mg active medicine tablet per 380 (400) gallons or 25 mg per 10 gallons In other words there are 40 10 gallon treatments per large tablet! Good thing a a many times higher dose shows no ill effects on corals because you would need lab grade equipment to break that 1 gram tablet up 40x. In reality this is ~¢17.5 per 10 gallon treatment at the hobby price of $7 per pill or $1.75 per 100 gallons and a 1/4 pill is reasonably measured. TSC's price for Ivermec® is roughly $40 per 50 mls a 10 gallon 200 mcg/l dose is ~.76ml or roughly 65 10 gallon treatments or ¢61 per dose or $6.10 per 100 gallons.

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Glean what you want from the above at your own risk; latter I may have time to look into the powder levamisole form.
 
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I don't know why I confused the Levamisole with Ivermec; they are different drugs. The threads I saw cunfused me. There is a reason I'm not the doctor in the house; too many blows to the head.
 
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