You probably do not want to use a sand filter on a reef system. They are basically a particulate filter that can support biological activity (nitrate issues). They are great for clarifing water, but that is about it. This might make them less useful for reef tanks where you might want some suspended materials in the water column of the aquaria.
The flows and backpressure issues make them more useful on larger systems, swimming pools, municipal water supplies and the like, where water flow is measured in hundreds or thousands of gallons per minute.