Yes, they generally don't play well. However, things such as size of the corals, water flow, carbon usage, and water changes all can have affect.
In my 265g reef I decided to remove my very large leathers after I couldn't grow sps. It would constantly wither and die even after consistent carbon changes. After removing the leathers, sps came back with a vengeance.
Having a small leather or 2 in your sps tank shouldn't have and effect though
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