The 'S' curve I am talking about would be two brachistochrone curves joined together in opposing orientation. A brachistochrone is part of a cycloid BTW. The funny thing is that Johan Bernoulli found this curve for other reasons, but thanks to the long line of mathematicians that were due to follow him and his brother Jacob, Daniel Bernoulli later found this curve's importance for fluid dynamics (Daniel is the one that came up with the Bernoilli equasions for fluid dynamics...I think, but I could be wrong because there is a while family of Bernoullis that were all mathematicians, and all had contributions in the fields of physics and fluid dynamics>>>Nicolaus I & II as well ). I just think its kind of funny how much that small group of brothers & sons contributed to calculus (of course, Jacob was hanging out with Newton at the time, and the older brothers were brought up learning from masters like Leibniz, Hook, and Boyle, and many others). In the end, their contributions to fluid dynamics are what makes protein skimmers possible...so if we were to follow the recent happenings of naming machines after their inventors (Durso, Stockman, etc), the protein skimmer should be named a Bernoulli machine.
Anyways, the best way for the bubbles to travel is with a gradual corve inward from the sides, and then another gradual curve upwards into the neck. This prevents 'launching' the bubbles into each other from multiple directions like with a flat sided reducer neck. Euroreef collection necks are a good example of this, and perhaps the reason why ERs and ASMs are 'soo similar' yet the ERs seem to just pull out more gunk.