All I know is when I began filling our 150g for the first time with for a fw leak chk, the entire time I skipped from one joist to the next and measure from floor to joist in the basement lol.
I installed ours directly over the center of our center bearing wall in the house. It isn't a steel I-beam that is in most current house but rather a big 2x8 header x4, over-lapped and sitting on steel posts every 8' the length of the house.
When we remodeled our kitchen last Fall, we opened up the area from kitchen to living room that would house our aquarium. I went overkill above and installed a double 12" LVL Microlam header, (had these leftover from a project), in the 10' space. This is obviously carrying the load from above, so I'm no engineer but I figured the basement beam is now primarily carrying our DT's load.
If you have any questions DO consult an engineer or at least chat with a buddy that might be in the construction field and ask their opinion. Don't take any chances.
IMO a floor wouldn't just all of a sudden fail and everything ends up in the basement. I believe during initial fill up you would notice all kinds of red-flags such as loud creaking and some noticeable bow-age/deflection...if ignored and continued to fill then maybe things might become a touch more dramatic

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One thing I DO sometimes get weirded out a bit about is when I have a ton of people hovering around the DT at once LOL. I find myself sometimes counting "Hmmm...1, 2, 3...10, 11...ok x 125-200lbs each..ooookkkk" lol.