Just to get back to drilling with water in-tank real quick.... I was in the exact same boat as you with regards to this. I didn't want to change my aquascape because I really liked it, and I was very tempted to drain half and drill.... After thinking about how much time and money I dumped into that glass box, I went with a new aquarium of the same dimensions. First attempt at drilling it and it split right down the back. It was at that moment that I was extremely relieved that I went that route, otherwise I would have had about 8 seconds to view my tank before the glass busted and water/corals flew everywhere. I know people have done it with water in tank before, just some food for thought though.
P.S. My aquascape is better than ever!