that is my idea, lay in the epoxy then drop the sheet in. probably do bottom first, then front and back, and finally the sides. each time rotating the tank so the side your working on is on the ground; then the epoxy can just set there, and lay the acrylic sheet into place. should be fully supported then. all the weight transfered straight through to the wood.
could be difficult to do on a MUCH larger tank. my future tank will be 12x4x4' which IMO is still workable and able to be stood on its ends as well as moved with enough helpers.
as for the corners, the sheets of acrylic should be all jointed nicely, if the cuts are done accuratly weldon 4 shouldnt be out of the question, with some weldon 16 for additional corner strength. but yeah, a corner peice of acrylic for the seams could be a very viable option for additional strength, probably a better choice if you were to try thinner acrylic walls.
if you wanted an acrylic viewing panel you could make the front panel a full size sheet of nescessary thickness and bond it right into the tank and be 100% water tight, wouldnt have to worry about siliconing it in.
I want a glass viewing panel for scratch resistance though. willing to sacrifice that bit of sturdiness for it.