PSA: PRIME safe to use with COPPER POWER

HumbleFish

Dr. Fish
Premium Member
First, a few disclaimers:

1. This only applies to using Seachem Prime with Copper Power.
2. I have not tested any other ammonia reducers with any other forms of copper. Seachem, for example, states right on their website that it is dangerous to mix any ammonia reducer with their Cupramine copper product.
3. The manufacturer of Coppersafe (Fritz) has told me that it is safe to use with ammonia reducers as well, but I have not independently verified this.

This all started when the manufacturer of Coppersafe (Fritz) informed me that their copper product was safe to use with Prime, Amquel, etc. This differs from what Seachem has always stated about Cupramine - that any ammonia reducer will turn it 10x more toxic. However, these are completely different forms of copper. Cupramine is "ionic copper" bound on amine, and an ammonia reducer has the potential to break that bound and reduce the Cupramine from the safe Cu2+ form to a very toxic Cu+ form. Coppersafe (and Copper Power) are both chelated coppers. A chelated copper solution is just a blend of two compounds. One is the copper sulfate granule, and the other is an ingredient that allows the copper granules to break down and stay in a liquid state. The ingredient that makes this happen is called a chelator, or sequestering agent.

After getting the green light/more confidence from a chemist about this, I began experimenting on fish by mixing Prime + Copper Power in a QT. I did this repeatedly on different batches of fish, got the copper level as high as 2.5 ppm, tested daily, dosed Prime daily and all the fish are still fine. Not once did I see a spike in the Cu level after dosing Prime using the Hanna High Range Copper Colorimeter (HI702).

So, I feel it is safe to use & recommend mixing Prime with Copper Power to control ammonia on an as needed basis.
 
P.S. Prime can also be used with General Cure and antibiotics. However, I would avoid dosing Prime in conjunction with liquid Prazipro due to the solubilizing agent it contains.
 
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