I have a small 10 gallon fuge on my 90 gallon tank. I dont think it really contributes to conditioning as I believe it to be drastically undersized to have an impact on water quality but it is a sanctuary for pods to reproduce. Having a leopard wrasse, dragonet and multiple anthias, this is a must for me. I also use it as a stress free environment with a rich, ample food source for new fish to get accustomed to the water parameters. IMO, it comes down to, why do you want a refugium? To help export nutrients, go as big as you possibly can. For pods, a 10 gallon tank can hold a ton of pods.