It's not really up to AB though. It's up to the shareholders (many of whom are AB employees). The actual family only owns about 4% of the business now.
I personally don't think it would be a huge deal. InBev would want a US based headquarters, and I would bet 100:1 odds that the AB campus is appealing in that regard. The brewery may not be efficient, but I'm sure InBev has done their homework and understands the potential pr fallout.
As it is, AB has pretty much saturated the US market. AB growth domestically would be pretty small over the short and long term. InBev is stronger internationally, so the partnership makes sense from a business perspective. If the takeover happens, I suspect layoffs would be small and only to improve the efficieny of the plants. There was an article last weekend that also explained how appealing it may be to Inbev to acquire workers such as those in STL, where the brewery and it's jobs are held in such high esteem.
I hope it doesn't happen though, and will not likely sell my stock (not much) to InBev's bid price. Some of what I've read says that InBev is not pleased with the financing terms they are hearing from the multiple banks they will need to use. But hey, I wouldn't try to borrow $50 billion and expect a good rate either.
