I just take mine for a dip in r/o then scrub with a toothbrush or similar to losen up all the particles from the mesh. I don't like to risk something like bleach because of the liklihood of poisoning my system. If you do use bleach, as Abengochea said, rinse thougoughly and I would even take it a step further and air dry completely to make sure all chlorine bleach residue is gone.