Just for the record, due to the fact that it's what I could get cheap at the time, my 5 gallon RDSB on my 55g tank is filled with Silica Play Sand. I have not noticed any particular problem, but have no real way to authoritatively say it hasn't caused a problem.
I should pick up a silica test and see if levels are higher then recommended.
Anyhow, the harm (or not) of using silica based sand in reef tanks is a highly debated issue. Recognized experts and pros in the field will go both ways on this issue. I personally don't think there is currently any definitive way of stating that it will or will not cause a problem.