CC will work well, provided enough manual cleaning is done. I use fine sand, now, since animals will do the cleanup for me. If CC is not cleaned carefully, it can trap a lot of organic debris and become a nitrate source, in my experience.
That much CC will require a lot of siphoning if you have much of a load in the tank. It really traps detritus and excess food if its not kept clean. Sand really takes care of itself once you get the right critters to keep it that way.
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