Sounds like it might be worth laying off the Coral Accel after the water change for a while.
Coral Accel contains hydrolyzed marine protein, marine lipids, potassium iodide, ascorbic acid (vitamin C), vitamin A propionate, vitamin A palmitate, sodium EDTA, tocopherol (vitamin E). I wonder which of these, if any, would cause the RTN? I'm no marine biologist, but it makes some sense that something could have accumulated over the past few weeks. I'm a skeptic of a lot of these additives. They don't seem to take into account the variables of each tank, and this one includes 3 antioxidant vitamins for which test kits aren't available. Could these have accumulated to toxic levels?
Sodium EDTA is an interesting compound. It binds to metals, such as nickel, copper, and iron, making them unavailable to react with other ingredients in a product. EDTA also sequesters calcium and magnesium from hard water. I wonder if this could be binding with any of the necessary elements in your water.