I think in larger numbers, they could be harmful. Just one or two shouldn't be an issue, though they can sting some corals. I have several acans which destroy any hydriods within reach of the sweeper tenticles. There dosent seem to be much information on the internet about them. The are carnivores, I fed a few just to see what the eat. Also, if your working in your aquarium while they are extended they will sting you. It's not too painful though.