No, it is not a proven problem. What is proven is uncured silicone is a problem, along with just about any uncured product. Is polyurethane with a mildew inhibitor harmful? Depends on if there is actually a mildew inhibitor in the "mix," where as in silicone there is no indication that such an additive is present, despite the advertising.
My question would be: what is the intended usage?
What is recommended for aquarium use is:
1-Part
Acetoxy Cure
100% silicone (no co-polymers in it)
FDA approved for food contact.
Appropriate for the purpose: sealants for sealing, adhesives for structural uses.
That said, polyurethane does bond to glass, in a manner similar to silicone. However, when looking at the data sheet for this particular product, we see some things that
could be unsettling:
"- 3MTM Marine Adhesive/Sealant Fast Cure 5200 is not recommended for the installation of glass, polycarbonate or acrylic windows that are not also mechanically fastened with a system designed by the manufacturer. Inconsistent adhesion of these unprimed substrates, specific design of the window and movement due to thermal expansion and flexing, may cause application failure."
So first we see that "aquarium" is outside the appropriate usage for this product. Secondly, we are not using windows, rather large chunks of plate glass, that in some cases are not mechanically fastened, and are subject to movement due to thermal expansion and flexing. I have also "read" (outside the hobby) of "some" cohesive issues with polyurethane adhesives, though the bond to glass is suitable. It is older information, so take it for what it is worth, as I can't give you the specifics.
Fair is fair, so what is your intended usage in the tank? I am not going to sit here and say "don't," without knowing what you have in mind. Though there
may not be any chemical ramifications, there could
possibly be some others. Myself, I would use something that is
known not to have these additional "complications." See above recommendation.
http://multimedia.3m.com/mws/mediaw...UqevTSevTSevTSeSSSSSS--&fn=Fast Cure 5200.pdf