Acrylic is lighter.... If you are going big, that would be a consideration. Acrylic can be buffed... Scratches removed... Yes, even underwater. Acrylic is clearer than regular glass but about the same as the starphire... Acrylic will bow and yes it can break. If you accidentally get ammonia on your acrylic, it will craze... (small cracks in the acrylic like a shattered windsheild). With acrylic, levelling is 'less' important as with glass, you will want to be sure your tank is PERFECTLY level. Acrylic will scratch easier, but glass will scratch as well. If you are REALLY careful when working with your tank, there is absolutely nothing wrong with acrylic. There are also some folks that say MH lights will 'melt' thier tank. If setup correctly, and ventilation is good, you should not have any problems with this. Acrylic will keep your tank heated better in the winter months as it is a better insulation than glass. However, this can be a disadvantage in the summer time. I've heard from both sides and met folks that are very happy with their acrylic tanks. There seems to be more maintenace with acrylic but there are benefits with both glass and acrylic.
Just some things to consider.
Guy