I don't run it 24/7 for a number of reasons, none of which are based on anything other than hunches.
1: I didn't want to over sterilize the water, I dose bacteria while the UV is off, hoping it is able to do that do that it do better without the sterilizer.
2: I want the bulbs to last longer. I hear your point about on/off cycles, but without some evidence am not convinced that one cycle a day will overcome 12 hours of non use. But I'm willing to be convinced otherwise.
3: Heat. I know its only 57 watts, but its more 57 watts to heat my tank during the day. I run it at night, saving heater use at night and chiller use during the day.