i can tell you this, which is ME, and IMO.. these are ok for a fish that doesnt have a bad case of whatever may need to be treated.. if its something you just noticed it may work, if its an existing condition that has not gotten better i wouldnt use it..these are good when used for new cuts, abrasions, new infections..when i had oscars/African cichlids it worked great for new open wounds, not existing ones, plus this is all i really used it for IME and a few others i know, it really didnt work well for anything else.. you are better off trying a powder type or pill form (maracyn, maracyn two, tetracycline)..and i would always treat anything in QT obviously..