I have a large (volleyball sized) pink bubble and it will inexplicably close up for a day or two from time to time.
If I were you I'd do some water changes over a couple of days, check all water params, check and clean all pumps to make sure flow is gentle but decent (as you intend it to be). If you have T5 make sure bulbs aren't too old. If it opens at all offer it a small hunk of clam and see if it responds. If it eats its fine.
If, in 2-3 days, it starts looking even worse give it an iodine dip.