500 is fine. I keep my aqauriums between 480 and 500 on averqage, with an average dkh of 13-14. Ph hovers 8-8.1 and my tanks are very healthy. I get great growth as well.
In relation to ALK, anything 17 and over is a worry factor. Below that, do not worry too much. Ca, the worst that happens is you start to coat your parts with Calc deposits. High Ca won;t kill anything other than equipment over a long time. Having a high Ca and high ALK in good relations is fine and healthy.
Like Angela stated, Oceanic is a mix that promotes growth and is high in CA and Mg. It's why I use it. Nothing wrong with other mixes, just a preference. IO and others I have to add stuff; Oceanic I mix and add to the tank.