Turn off the supply, remove the filters, unhook the 1/4" line from the last carbon up to the RO membrane, put 3 tablespoons of regular unscented bleach in the first housing and reinstall the housings minus filters. Turn the water back on and run a few gallons out the 1/4" line you disconnected into a bucket or the sink. Remove the housings, dump them out, reinstall the filters and housings,turn the water on and erefill the housings purging air and then hook back up to the RO membrane and you are done.
Its important to disinfect the housings at least once per year but I recommend doing it at 6 months, every time you change filters.