Personally, I'll take wet skimming over dry skimming anyday. If you have a full blown sps tank, wet skimming is a great way to keep a nutrient problem from getting out of hand fast.
I don't believe in starving my fish for the sake of the corals, so I feed heavily, let the fish and corals get what they can, and then wet skim to grab as much out of the water column as possible. I'm not trying to wet skim like some who use it to an extreme as a water change means, but if there's any buildup in the skimmer neck in a few days' time, I know I'm skimming too dry.
And to answer the OP's question, I believe it's only possible to over skim if you have a skimmer rated for twice your tank's water volume and still feed only enough to barely keep your fish alive. Reefs in the wild have much cleaner water than we can replicate in a closed system, so feed the fish and skim heavily is my mantra.
Just my two cents.