I've always had acrylic tanks due to living in earthquake country and small kids. As far as the ease of it scratching there is no doubt you will get some.
Although, over the last 8 years of owning acrylic tanks, I've kind of become pretty good at removing minor to major scratches with fine sand paper pads I've gotten from Sculpt.com.
When I had my 60G and was able to reach into the tank's bottom I used to get the micro mesh kits 4"x6"? pads (3600 grit all the way to 12000) that were meant for sanding marble. I tested it on a smaller 30G filled with some livestock and never saw any negative side effects (skimmer did go a little nuts). I then used it on my 60 DT and all the scratches came out as if they never happened! Never saw any negative side effects from any of the fish/corals.
When I upgraded to my current 180G it was a lot harder to reach the scratches near the bottom of the tank so I looked into the wooden pen kits they had. They came in these little 2"x2" pad that I cut out a hole for in my cleaner magnet (to keep them from sliding out). It also came with these 150-600 grit tongue depresser type sanding sticks for the deeper scratches. This worked like a charm and I was able to get some really deep scratches polished out due to the stronger cleaner magnet. The only way you can really tell that the scratches are there is when you put your nose to the panes (and really look for them) but otherwise, people always think that I just got my acrylic tank since it's pretty scratch free.
So there goes the problem of scratches in acrylics pretty much solved for me. I also have a wide openings on my 180G since I had it custom made with a thicker acrylic top to support it. I believe they're like 30"x18" openings.
HTHs,
Minh