I have a closed loop with 12 ports, 9 on the back and 3 on the bottom. The back use orbital bulkheads and the bottom terminate in Ts. Two Dart pumps power the CLM and a Snapper is on the return from the sump. The return has two orbitals, near the top of the overflows. I also have a full size wavebox and I still have dead spots.
One one of the orbitals I changed out and put twin locline so that I could direct flow where I needed it. Some of the outlets have to be throttled back as they put out too much flow and my sand blows all over the place.
My dead spots are right in front of my SPS and near one of my bottom outlets. I just added a Koralia 3 pumping off the back wall toward the corner. I hope this wraps around the front and adds more flow at the sand bed without moving the substrate around.