A 2" sand bed should probably be vacuumed, unless it's a very fine grain like Southdown. A very fine sand at that depth could have anaerobic zones, and you wouldn't want to disturb them.
Supplementation is pretty pointless on a softy tank, especially if you're doing regular water changes -- that's all you need. You should never supplement anything you can't test for -- especially things like calcium and magnesium which can have a profound effect on your alkalinity and maybe even pH if you do it wrong.
The most important task, IMO, for a healthy looking tank is having as much flow (preferrably random) in the tank as your livestock can handle. Good flow maximizes effectiveness of LR, maximizes effectiveness of the skimmer, and makes it difficult for algae to take root anywhere.
Clean up crew opinions vary wildly. It's important to realize that any janitor will eat something, but then release detritus of their own -- albeit less. Snails eat algae, go doo doo, and algae utilizes the doo doo to grow again -- the net effect is just whatever energy the snail used to move around. For me, I like a small clean up crew.
I think hermits are a waste of money -- in exchange for a critter that basically eats extra food or dead fish you get snail killing. Yes, they will kill live snails for their shells, especially cerith snails -- assumedly because cerith shells are perfect for hermit bodies. Some scarlet hermits will eat hair algae, but beyond that you don't need hermits if you don't overfeed and you get dead fish out of the tank. You have to have some sort of snail to deal with film algae on the glass, and large mexican turbos or astreas. It's also good to have some sort of sand sifter / detritus eater -- and ceriths do both. It's also good to have shrimp of some sort, and if you have aiptasia peppermints are the ticket, if you don't than cleaners so you can get the added benefit of fish parasite removal.
I have a 125, 32X tank turnover (pretty strong for a mixed reef with sand), and my cleanup crew is 6 Mexican Turbos, 3 Scarlet Hermits, 12 Ceriths, 4 Peppermint Shrimp, and 2 Cleaner Shrimp.
If you have enough flow, you just don't need all those janitors...