Over the holidays I built an AMD system and an Intel system and they were to do the same thing (one for me, one for the GF). After that debacle, and after all the hassle with getting things setup, I would definately go AMD.
Between the Intel E6400 I built and the AMD 5000+ I built (both with 4 gig RAM and 7900 graphics cards), the AMD was less of a hassle and has worked smoother. I find that AMD is more bang for the buck in the long run and we use these computers for about everything.
Just my .02