Twitching is usually a sign of flukes. A freshwater dip may help if you can catch him. Prazipro works too for flukes. Some say it's reef safe... I've never personally used it in a reef.
Some sort of parasite is most likely. You'll need to look closely and give a description of anything unusual. There are a lot it could be and there are different treatments for different things. With the info you give us we might be able to narrow down what it could be.
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