Prazipro use

100% water change isn't needed I think the bottle says 60% maybe? I can't remember and I don't have a bottle handy to tell you for sure
 
I usually do a partial WC (20-30%) between treatments.

Same here. usually the 6th day after dosing, i'll do about 30% water change. I typically time my doses to "expire" about the same time i would normally need to do a waterchange in my QT to make it easier on myself.
 
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