here is one
"As with most cephalopod species that have been cultured to date, two areas of further research
are needed... the second is solving the problem of low fertility
of captive cultured adults"
Minton J.W., Walsh L.S., Lee P.G. and J.W. Forsythe 2001. First multi-generation culture of the tropical cuttlefish Sepia pharaonis Ehrenberg, 1831. Aquaculture International. 9 : pp.379-392
Download: 7479.pdf
This is where I got the idea that there is a problem. Then I read the doctors paper about cardinal fish. Of course cardinal fish are not cephalopods but i think the problem might have a similar solution. Here is his paper, correct me if I am wrong doctor, i believe this list of numbers is read last to first.
"The average numbers of babies released was 20 [r=10, 12, 13, 15, 17, 17, 19, 20, 21, 21, 21, 22, 22, 24, 25, 28, 31, 37]. Interestingly, the brood size was larger during the first one or two breedings, and after the first year all my brood sizes dropped to below 20 babies/brood"