I had a 5 gallon tank and it is tough to keep anything in it other than some coral frags, maybe a shrimp or two and a snail or two .... BUT it is really cool once it settles and fills out. I would say have bottled water sitting your work desk (sealed - ro purified) and use that as top off water (shake - open cap - blow some bubbles in it with a straw and let sit) ...... also the water changes can be a real biotch @ the office (if you mean work office and not home office) .....
otherwise as long as you don't mind no fish and people asking why no fish .... then I would say - Go for it!